SCHEMBL17052018

SCHEMBL17052018

CCCCCCCCC1(CCCCCCCC)c2cc(C)ccc2-c2ccc(-c3cc(-c4cccc(-c5cc(-c6ccc(-c7ccc(C)cc7)cc6)nc(-c6ccccc6)n5)c4)nc(-c4ccc(C#N)cc4)n3)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 4/20 0.39
ABCB1 P08183 2/20 0.39
KDM4E B2RXH2 3/20 0.38
ADORA2A P29274 2/20 0.38
ADORA1 P30542 2/20 0.38
HPGD P15428 2/20 0.38
PPARG P37231 1/20 0.38
NCOA2 Q15596 1/20 0.38
NCOA1 Q15788 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
ALDH1A3 P47895 1/20 0.36
ABCC1 P33527 1/20 0.36
MAPT P10636 2/20 0.36
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
AGTR1 P30556 1/20 0.35
MYC P01106 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17051772 0.99 ABCG2 (0.38) ABCG2ABCB1KDM4EADORA2AADORA1
SCHEMBL17051771 0.98 ABCG2 (0.38) ABCG2ABCB1KDM4EADORA2AADORA1
SCHEMBL17052019 0.98 ABCG2 (0.38) ABCG2ABCB1KDM4EADORA2AADORA1
SCHEMBL17051986 0.94 TSHR (0.39) ABCG2ABCB1KDM4EADORA2AADORA1
SCHEMBL17051694 0.93 TSHR (0.39) ABCG2ABCB1KDM4EHPGDPPARG
SCHEMBL17052016 0.92 AGTR1 (0.39) KDM4EADORA1HPGDNPSR1ALDH1A3
SCHEMBL17051769 0.91 AGTR1 (0.39) KDM4EADORA1HPGDNPSR1ALDH1A3
SCHEMBL17052026 0.91 MEN1 (0.39) KDM4EADORA1HPGDNPSR1MAPT
SCHEMBL17052024 0.91 MEN1 (0.39) KDM4EADORA1HPGDNPSR1ALDH1A3
SCHEMBL17051781 0.91 MEN1 (0.39) KDM4EADORA1HPGDNPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038143-B2 Polymer compound, material for electronic elements, material for organic electroluminescent elements, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-07-31 US disclosed
US-20150249215-A1 POLYMER COMPOUND, MATERIAL FOR ELECTRONIC ELEMENTS, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed