SCHEMBL170522

SCHEMBL170522

CC(=O)Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 3/20 0.62
MAPT P10636 4/20 0.58
KDM4E B2RXH2 3/20 0.58
ALDH1A1 P00352 2/20 0.58
MYC P01106 1/20 0.58
POLB P06746 3/20 0.57
AKR1C3 P42330 2/20 0.57
HSD17B10 Q99714 2/20 0.57
PKM P14618 2/20 0.57
TSHR P16473 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
AKR1C2 P52895 1/20 0.57
AKR1C1 Q04828 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.56
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CYP2D6 P10635 1/20 0.54
ATM Q13315 1/20 0.54
CSNK2A1 P68400 1/20 0.53
CA12 O43570 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30076649 1.00 KDM4C (0.62) KDM4CMAPTKDM4EALDH1A1MYC
SCHEMBL11800290 0.98 KDM4C (0.60) KDM4CMAPTKDM4EALDH1A1MYC
SCHEMBL30621955 0.87 SMN1; SMN2 (0.57) KDM4CMAPTKDM4EALDH1A1MYC
SCHEMBL925741 0.87 SMN1; SMN2 (0.57) KDM4CMAPTKDM4EALDH1A1MYC
SCHEMBL729994 0.85 SMN1; SMN2 (0.70) MAPTKDM4EALDH1A1MYCPOLB
SCHEMBL2500845 0.85 MYC (0.61) MAPTKDM4EALDH1A1MYCPOLB
SCHEMBL12041031 0.85 EPHX2 (0.61) KDM4CMAPTKDM4EALDH1A1POLB
SCHEMBL11804736 0.84 SMN1; SMN2 (0.68) MAPTKDM4EALDH1A1MYCPOLB
SCHEMBL551783 0.84 SMN1; SMN2 (0.54) KDM4CMAPTKDM4EALDH1A1POLB
SCHEMBL7077248 0.83 KDM4C (0.68) KDM4CMAPTKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117867067-A Buffer solution, in-vitro diagnostic reagent and detection kit for improving detection sensitivity of bovine viral diarrhea virus 杭州奥泰生物技术股份有限公司 2024-04-12 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-113816940-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-21 CN claimed
CN-113754634-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-07 CN claimed
US-20210015092-A1 STABILIZATION OF WHOLE BLOOD AT ROOM TEMPERATURE ROCHE DIAGNOSTICS OPERATIONS, INC. 2021-01-21 US claimed
CN-105939601-B Stabilization of whole blood at room temperature 豪夫迈·罗氏有限公司 2020-03-10 CN claimed
EP-3099163-A1 STABILIZATION OF WHOLE BLOOD AT ROOM TEMPERATURE F. Hoffmann-La Roche AG (CH) 2016-12-07 EP claimed
US-20160324144-A1 STABILIZATION OF WHOLE BLOOD AT ROOM TEMPERATURE ROCHE DIAGNOSTICS GMBH (DE) 2016-11-10 US claimed
US-20160045442-A1 STABLE PHARMACEUTICAL COMPOSITIONS OF MESALAMINE CADILA HEALTHCARE LTD (IN) 2016-02-18 US claimed
WO-2015113988-A1 STABILIZATION OF WHOLE BLOOD AT ROOM TEMPERATURE F. HOFFMANN-LA ROCHE AG (CH) 2015-08-06 WO claimed
EP-1478229-A4 IMPROVED SYNTHESIS OF POLYANHYRIDES UNIV RUTGERS (US) 2005-11-23 EP claimed
CN-1684582-A Improved synthesis of polyanhydrides UNIV RUTGERS (US) 2005-10-19 CN claimed
WO-2005072113-A2 COMPOSITIONS AND METHODS OF TREATMENT FOR INFLAMMATORY DISEASES HARTY RICHARD F (US) 2005-08-11 WO claimed
US-20050159396-A1 Compositions and methods of treatment for inflammatory diseases BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA, THE 2005-07-21 US claimed
US-20050131199-A1 Synthesis of polyanhydrides RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2005-06-16 US claimed
EP-1478229-A2 IMPROVED SYNTHESIS OF POLYANHYRIDES Rutgers, The State University (US) 2004-11-24 EP claimed
WO-2003046034-A2 IMPROVED SYNTHESIS OF POLYANHYRIDES RUTGERS, THE STATE UNIVERSITY (US) 2003-06-05 WO claimed
EP-0236329-A1 AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS ITAL-FARMACO S.p.A. (IT) 1987-09-16 EP claimed
WO-1986003199-A1 AMINO-SALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS ITALFARMACO S.P.A. (IT) 1986-06-05 WO claimed
WO-1981002672-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR THE TREATMENT OF COLITIS ULCEROSA AND CROHN'S DISEASE FERRING FARMA LAB (DK) 1981-10-01 WO claimed