Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | MB | P02144 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30621955 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBPKMALDH1A1CA1 | |
| SCHEMBL925741 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBPKMALDH1A1CA1 | |
| SCHEMBL30076649 | 0.84 | KDM4C (0.62) | SMN1; SMN2POLBPKMALDH1A1CA1 | |
| SCHEMBL170522 | 0.84 | KDM4C (0.62) | SMN1; SMN2POLBPKMALDH1A1CA1 | |
| SCHEMBL11204834 | 0.83 | POLB (0.54) | SMN1; SMN2POLBPKMALDH1A1CA1 | |
| SCHEMBL11800290 | 0.82 | KDM4C (0.60) | SMN1; SMN2POLBPKMALDH1A1CA1 | |
| SCHEMBL7380689 | 0.82 | SIRT2 (0.55) | SMN1; SMN2SIRT2ALDH1A1CA1CA2 | |
| SCHEMBL13254952 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBSIRT2MAPTKDM4E | |
| SCHEMBL7858888 | 0.81 | KDM4C (0.49) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL27676821 | 0.81 | CYP3A4 (0.53) | SMN1; SMN2POLBALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440034-A1 | HIGH OIL CONTENT PLANTS | Bayer BioScience N.V. (BE) | 2012-04-18 | — | — | EP | disclosed |
| US-20120084883-A1 | High Oil Content Plants | BAYER CROPSCIENCE N.V. (BE) | 2012-04-05 | — | — | US | disclosed |
| US-8110570-B2 | Modulators of acetyl-coenzyme A carboxylase and methods of use thereof | CROPSOLUTION, INC. (US) | 2012-02-07 | — | — | US | disclosed |
| EP-2310015-A1 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | Cropsolution, Inc. (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010142424-A1 | HIGH OIL CONTENT PLANTS | BAYER BIOSCIENCE N.V. (BE) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010008521-A1 | MODULATORS OF ACETYL-COENZYME A CARBOXYLASE AND METHODS OF USE THEREOF | CROPSOLUTION, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| US-20100009982-A1 | Modulators of Acetyl-Coenzyme A Carboxylase and Methods of Use Thereof | CROPSOLUTION, INC. | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009982-A1 | Modulators of Acetyl-Coenzyme A Carboxylase and Methods of Use Thereof | ACACA, ACAT1, ACACB | SMN1; SMN2 3898/4885POLB 3154/4885PKM 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.