Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 6/20 | 0.42 |
| ▸ | CTSC | P53634 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545547 | 1.00 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL17023724 | 1.00 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL18576565 | 1.00 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL18555502 | 1.00 | CFD (0.42) | CFDCTSCMEN1KMT2ACHRM1 | |
| Hydrochloric Acid SCHEMBL17023497 | 0.99 | CFD (0.41) | CFDCTSCMEN1KMT2ACHRM1 | |
| Hydrochloric Acid SCHEMBL29544869 | 0.99 | CFD (0.41) | CFDCTSCMEN1KMT2ACHRM1 | |
| Hydrochloric Acid SCHEMBL17046887 | 0.99 | CFD (0.41) | CFDCTSCMEN1KMT2ACHRM1 | |
| SCHEMBL20329698 | 0.91 | CFD (0.40) | CFDMEN1KMT2ACHRM1POLB | |
| SCHEMBL22355134 | 0.91 | CFD (0.40) | CFDMEN1KMT2ACHRM1POLB | |
| SCHEMBL17039238 | 0.89 | CFD (0.37) | CFDCTSCCHRM1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015130838-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-03 | — | — | WO | disclosed |