SCHEMBL1705328

SCHEMBL1705328

C=C(C)C(=O)Nc1cccc(S(N)(=O)=O)c1.C=C(C)C(=O)Nc1ccccc1S(N)(=O)=O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 15/20 0.53
CA2 P00918 15/20 0.53
CA12 O43570 11/20 0.53
CA9 Q16790 11/20 0.53
MAPT P10636 2/20 0.53
POLB P06746 2/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
TDP1 Q9NUW8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396033 0.89 CA1 (0.61) CA1CA2CA12CA9MAPT
SCHEMBL395455 0.86 CA1 (0.58) CA1CA2CA12CA9
SCHEMBL29733673 0.86 CA1 (0.58) CA1CA2CA12CA9
SCHEMBL6277650 0.86 CA1 (0.58) CA1CA2CA12CA9
Benzenesulfonamide SCHEMBL11842417 0.81 CA1 (0.57) CA1CA2CA12CA9MAPT
Benzenesulfonamide SCHEMBL27997661 0.79 CA1 (0.59) CA1CA2CA12CA9MAPT
SCHEMBL11646832 0.79 TDP1 (0.50) CA1CA2CA12CA9MAPT
SCHEMBL7597973 0.78 TDP1 (0.64) CA1CA2CA12CA9MAPT
SCHEMBL1811660 0.76 TDP1 (0.62) CA1CA2CA12CA9MAPT
SCHEMBL11842413 0.75 TDP1 (0.56) CA1CA2CA12CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399783-B1 METHOD OF PROCESSING LITHOGRAPHIC PRINTING PLATE PRECURSORS KODAK GRAPHIC COMM GMBH (DE) 2013-01-09 EP disclosed
EP-1545878-B2 THERMALLY SENSITIVE MULTILAYER IMAGEABLE ELEMENT EASTMAN KODAK CO (US) 2012-04-18 EP disclosed
EP-1545878-B1 THERMALLY SENSITIVE MULTILAYER IMAGEABLE ELEMENT KODAK POLYCHROME GRAPHICS LLC (US) 2006-09-13 EP disclosed
EP-1444552-B8 METHOD FOR REUSE OF LOADED DEVELOPER KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-06-07 EP disclosed
EP-1444552-B1 METHOD FOR REUSE OF LOADED DEVELOPER KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-04-19 EP disclosed
US-6899992-B2 Polymerizable compounds with quadruple hydrogen bond forming groups KODAK POLYCHROME GRAPHICS LLC (US) 2005-05-31 US disclosed
US-6858359-B2 Scuff resistance KODAK POLYCHROME GRAPHICS, LLP (US) 2005-02-22 US disclosed
US-6855487-B2 Method and apparatus for refreshment and reuse of loaded developer KODAK POLYCHROME GRAPHICS, LLC (US) 2005-02-15 US disclosed
US-6852464-B2 Coating underlayer over a hydrophilic surface of a substrate; coating imageable layer over underlayer; heating KODAK POLYCHROME GRAPHICS, LLC (US) 2005-02-08 US disclosed
US-6849372-B2 Forming thermally imageable composite elements which provide developer resistance in desired regions, while maintaining white light desensitivity and durability. KODAK POLYCHROME GRAPHICS (US) 2005-02-01 US disclosed
EP-1291172-A2 A multi-layer thermally imageable element Kodak Polychrome Graphics LLC (US) 2003-03-12 EP disclosed
US-20030036024-A1 Developer for alkaline-developable lithographic printing plates EASTMAN KODAK COMPANY 2003-02-20 US disclosed
US-20030031948-A1 Method of processing lithographic printing plate precursors FPC INC. 2003-02-13 US disclosed
EP-1268660-A1 LITHOGRAPHIC PRINTING PLATE HAVING HIGH CHEMICAL RESISTANCE Kodak Polychrome Graphics Company Ltd. (US) 2003-01-02 EP disclosed
WO-2002101469-A1 METHOD OF PROCESSING LITHOGRAPHIC PRINTING PLATE PRECURSORS KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2002-12-19 WO disclosed
WO-2002093264-A1 DEVELOPER FOR ALKALINE-DEVELOPABLE LITHOGAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2002-11-21 WO disclosed
US-6358669-B1 SUBSTRATE WITH HYDROPHILIC SURFACE, OVERCOATING KODAK POLYCHROME GRAPHICS LLC 2002-03-19 US disclosed
WO-2002014071-A1 THERMAL DIGITAL LITHOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS COMPANY LTD (US) 2002-02-21 WO disclosed
US-6294311-B1 UNDERLAYER CONTAINS A COMBINATION OF POLYMERIC MATERIALS THAT PROVIDES RESISTANCE BOTH TO FOUNTAIN SOLUTION AND TO AGGRESSIVE WASHES, SUCH AS A UV WASH; CAN BE USED IN EITHER THERMALLY IMAGEABLE OR PHOTOCHEMICALLY IMAGEABLE ELEMENTS. KODAK POLYCHROME GRAPHICS LLC 2001-09-25 US disclosed
WO-2001046318-A1 LITHOGRAPHIC PRINTING PLATE HAVING HIGH CHEMICAL RESISTANCE KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2001-06-28 WO disclosed