SCHEMBL1811660

SCHEMBL1811660

C=C(C)C(=O)Nc1cccc(S(=O)(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.62
CASR P41180 3/20 0.49
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CA1 P00915 6/20 0.45
CA2 P00918 6/20 0.45
CA12 O43570 4/20 0.45
CA9 Q16790 4/20 0.45
MAPT P10636 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
PKM P14618 2/20 0.44
POLB P06746 1/20 0.43
CASP6 P55212 1/20 0.43
GPR35 Q9HC97 1/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzenesulfonamide SCHEMBL11842417 0.91 CA1 (0.57) TDP1CASRCA1CA2CA12
SCHEMBL7597973 0.89 TDP1 (0.64) TDP1LMNASMN1; SMN2CA1CA2
SCHEMBL396033 0.86 CA1 (0.61) TDP1CA1CA2CA12CA9
SCHEMBL393893 0.85 TDP1 (0.59) TDP1LMNASMN1; SMN2CA1CA2
SCHEMBL397453 0.84 KMT2A (0.59) TDP1LMNASMN1; SMN2MAPTPKM
SCHEMBL3033845 0.83 PKM (0.58) CASRLMNASMN1; SMN2PKMPOLB
SCHEMBL1098272 0.83 TDP1 (0.79) TDP1RXFP1POLBGPR35
SCHEMBL11842413 0.82 TDP1 (0.56) TDP1LMNASMN1; SMN2CA1CA2
SCHEMBL396170 0.82 TDP1 (0.56) TDP1LMNACA12CA9MAPT
SCHEMBL27404350 0.82 TDP1 (0.56) TDP1LMNASMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3112401-A1 ION-EXCHANGE MEMBRANE AND METHOD FOR PRODUCING SAME Fujifilm Corporation (JP) 2017-01-04 EP disclosed
CN-103547969-B Toner 佳能株式会社 2016-06-22 CN disclosed
EP-2501733-B1 RESIN FOR TONERS, AND TONER CANON KK (JP) 2014-03-05 EP disclosed
EP-2501733-A1 RESIN FOR TONERS, AND TONER Canon Kabushiki Kaisha (JP) 2012-09-26 EP disclosed
US-20120172562-A1 RESIN FOR TONERS, AND TONER CANON KABUSHIKI KAISHA (JP) 2012-07-05 US disclosed
WO-2011062289-A1 RESIN FOR TONERS, AND TONER CANON KABUSHIKI KAISHA (JP) 2011-05-26 WO disclosed