Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055396 | 1.00 | PPARA (0.54) | PPARAPPARGSOAT2SOAT1EPHX2 | |
| Bromide SCHEMBL9816169 | 0.99 | PPARA (0.53) | PPARAPPARGSOAT2SOAT1EPHX2 | |
| Bromide SCHEMBL9816176 | 0.99 | PPARA (0.53) | PPARAPPARGSOAT2SOAT1EPHX2 | |
| SCHEMBL28826330 | 0.92 | PPARG (0.48) | PPARAPPARGFAAHALDH1A1LMNA | |
| SCHEMBL2238586 | 0.84 | PPARA (0.52) | PPARAPPARGSOAT2SOAT1EPHX2 | |
| SCHEMBL18140030 | 0.83 | PPARG (0.44) | PPARAPPARGFAAHALDH1A1LMNA | |
| SCHEMBL18140712 | 0.83 | PPARG (0.44) | PPARAPPARGFAAHALDH1A1LMNA | |
| SCHEMBL18139546 | 0.83 | PPARG (0.44) | PPARAPPARGFAAHALDH1A1LMNA | |
| SCHEMBL18140944 | 0.83 | PPARG (0.44) | PPARAPPARGFAAHALDH1A1LMNA | |
| SCHEMBL18141571 | 0.83 | PPARG (0.44) | PPARAPPARGFAAHALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230404977-A1 | MODULATORS OF GTPASES AND THEIR USE | UNM RAINFOREST INNOVATIONS (US) | 2023-12-21 | — | — | US | disclosed |
| US-11672779-B2 | Modulators of GTPases and their use | UNM RAINFOREST INNOVATIONS (US) | 2023-06-13 | — | — | US | disclosed |
| US-20210212989-A1 | MODULATORS OF GTPASES AND THEIR USE | UNM RAINFOREST INNOVATIONS (US) | 2021-07-15 | — | — | US | disclosed |
| US-10857130-B2 | Modulators of GTPases and their use | UNM RAINFOREST INNOVATIONS (US) | 2020-12-08 | — | — | US | disclosed |
| US-20170182002-A1 | MODULATORS OF GTPASES AND THEIR USE | UNM RAINFOREST INNOVATIONS | 2017-06-29 | — | — | US | disclosed |
| US-20150335619-A1 | Modulators of GTPases and Their Use | STC UNM (US) | 2015-11-26 | — | — | US | disclosed |
| US-9125899-B1 | Modulators of GTPases and their use | STC.UNM (US) | 2015-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335619-A1 | Modulators of GTPases and Their Use | CDC42, RAC1, ROCK1 | PPARA 4262/4885PPARG 3517/4885SOAT2 1194/4885 |
| US-20210212989-A1 | MODULATORS OF GTPASES AND THEIR USE | CDC42, RAC1, ROCK1 | PPARA 4262/4885PPARG 3517/4885SOAT2 1194/4885 |
| US-20170182002-A1 | MODULATORS OF GTPASES AND THEIR USE | CDC42, RAC1, ROCK1 | PPARA 4272/4885PPARG 3427/4885SOAT2 1090/4885 |
| US-11672779-B2 | Modulators of GTPases and their use | CDC42, RAC1, ROCK1 | PPARA 4272/4885PPARG 3427/4885SOAT2 1090/4885 |
| US-20230404977-A1 | MODULATORS OF GTPASES AND THEIR USE | CDC42, RAC1, ROCK1 | PPARA 4272/4885PPARG 3427/4885SOAT2 1090/4885 |
| US-10857130-B2 | Modulators of GTPases and their use | CDC42, RAC1, ROCK1 | PPARA 4272/4885PPARG 3427/4885SOAT2 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.