Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585335 | 1.00 | GAA (0.53) | GAAATMKMT2ASLC6A9ESR1 | |
| SCHEMBL22770076 | 0.85 | ATM (0.39) | GAAATMKMT2AMEN1MAPT | |
| SCHEMBL8805155 | 0.84 | GAA (0.56) | GAAKMT2AESR1CHEK2MEN1 | |
| SCHEMBL227491 | 0.84 | GAA (0.65) | GAAKMT2AESR1MEN1MAPT | |
| SCHEMBL28973546 | 0.84 | GAA (0.65) | GAAKMT2AESR1MEN1MAPT | |
| SCHEMBL3858791 | 0.84 | GAA (0.65) | GAAKMT2AESR1MEN1MAPT | |
| SCHEMBL8496291 | 0.82 | GAA (0.54) | GAAKMT2AESR1CHEK2MEN1 | |
| SCHEMBL4191435 | 0.81 | GAA (0.53) | GAAATMKMT2AESR1CHEK2 | |
| SCHEMBL1349907 | 0.81 | ATM (0.38) | GAAATMKMT2ACYP2D6AOC3 | |
| SCHEMBL14528193 | 0.80 | GAA (0.53) | GAAACP3SLC6A2SLC6A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015128878-A1 | NOVEL BENZOXAPHOSPHOLE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-09-03 | — | — | WO | disclosed |