Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11890778 | 0.86 | TSHR (0.50) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17387566 | 0.84 | POLB (0.52) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13713464 | 0.83 | POLB (0.49) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13448552 | 0.83 | POLB (0.48) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6938181 | 0.83 | KMT2A (0.50) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26972369 | 0.81 | POLB (0.47) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16093641 | 0.81 | POLB (0.47) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL402936 | 0.81 | POLB (0.47) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24774944 | 0.80 | PIK3CD (0.50) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14865347 | 0.80 | POLB (0.49) | TSHRPOLBKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670764-B1 | C-28 AMINES OF C-3 MODIFIED BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-09-02 | — | — | EP | disclosed |