Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806923 | 0.95 | ADRA1D (0.47) | POLBKMT2AGAATSHRKDM4E | |
| SCHEMBL15024786 | 0.94 | ADRA1D (0.46) | POLBKMT2AGAATSHRKDM4E | |
| SCHEMBL15024716 | 0.91 | KMT2A (0.46) | POLBKMT2AGAATSHRSMN1; SMN2 | |
| SCHEMBL27984826 | 0.88 | POLB (0.47) | POLBKMT2AGAATSHRMEN1 | |
| SCHEMBL15024810 | 0.85 | RAB9A (0.43) | POLBKMT2AGAATSHRMEN1 | |
| SCHEMBL15024708 | 0.85 | ALDH1A1 (0.49) | KMT2AGAATSHRPIK3CDALDH1A1 | |
| SCHEMBL7342563 | 0.84 | KMT2A (0.49) | POLBKMT2ATSHRMEN1ADRA1D | |
| SCHEMBL13713464 | 0.84 | POLB (0.49) | POLBKMT2ATSHRMEN1ADRA1D | |
| SCHEMBL11515165 | 0.84 | GAA (0.53) | POLBKMT2AGAATSHRSMN1; SMN2 | |
| SCHEMBL6938181 | 0.83 | KMT2A (0.50) | POLBKMT2ATSHRMEN1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662004-B | Novel rebamipide prodrug, method for producing same, and usage thereof | 三进制药株式会社 | 2017-04-19 | — | — | CN | disclosed |
| US-9512325-B2 | Compositions comprising a reactive monomer and uses thereof | ISP INVESTMENTS LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-20130150481-A1 | COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF | HERCULES LLC | 2013-06-13 | — | — | US | disclosed |
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |