SCHEMBL17059016

SCHEMBL17059016

CCCCCCOc1ccc(C(=O)OC2CCC(C)CC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.56
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
THRA P10827 1/20 0.55
THRB P10828 1/20 0.55
PLA2G4B P0C869 5/20 0.55
RARB P10826 3/20 0.52
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
NPC1 O15118 1/20 0.51
LMNA P02545 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
PLA2G4A P47712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17059039 0.99 HPGD (0.57) HPGDTP53TSHRTHRATHRB
SCHEMBL2451370 0.91 HPGD (0.55) HPGDTP53TSHRPLA2G4BRARB
SCHEMBL10033674 0.91 HPGD (0.55) HPGDTP53TSHRPLA2G4BRARB
SCHEMBL9591789 0.89 HPGD (0.51) HPGDTP53TSHRTHRATHRB
SCHEMBL9591775 0.89 HPGD (0.51) HPGDTP53TSHRTHRATHRB
SCHEMBL14016041 0.88 TP53 (0.53) TP53TSHRTHRATHRBPLA2G4B
SCHEMBL9591784 0.87 HPGD (0.49) HPGDTP53TSHRTHRATHRB
SCHEMBL5961805 0.86 PARP10 (0.50) HPGDNPC1LMNA
SCHEMBL2020857 0.86 TP53 (0.55) TP53TSHRTHRATHRBPLA2G4B
SCHEMBL9942262 0.86 TP53 (0.55) TP53TSHRTHRATHRBPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500790-B2 Optical film, circularly polarizing plate, and image display device Konica Minolta, Inc. (JP) 2016-11-22 US disclosed
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE SUN2, HTR3D, CRY1 HPGD 2134/4885TP53 3261/4885TSHR 2612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.