Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 2/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.44 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 2/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20733040 | 0.83 | PARP1 (0.44) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL18544879 | 0.83 | GAK (0.44) | PARP1CCNCCDK8GAKRIPK2 | |
| Iodide SCHEMBL11565912 | 0.81 | GAK (0.43) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL599975 | 0.79 | PARP1 (0.44) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL599869 | 0.79 | DYRK1B (0.47) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL18970831 | 0.79 | PARP1 (0.44) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL29915158 | 0.79 | DYRK1B (0.47) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL14075851 | 0.79 | SMN1; SMN2 (0.51) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL31355748 | 0.79 | SMN1; SMN2 (0.51) | PARP1CCNCCDK8GAKRIPK2 | |
| SCHEMBL18544878 | 0.79 | HTR1A (0.54) | PARP1KDM4EMAPTHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170092867-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-03-30 | — | — | US | disclosed |
| US-20170054091-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-02-23 | — | — | US | disclosed |
| EP-2566477-B1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2015-09-02 | — | — | EP | disclosed |