Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 16/20 | 0.55 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059626 | 0.88 | EGFR (0.62) | EGFRERBB2ERBB4 | |
| SCHEMBL17059649 | 0.88 | EGFR (0.57) | EGFRERBB2ERBB4 | |
| SCHEMBL17059658 | 0.83 | CSNK1A1 (0.58) | EGFR | |
| SCHEMBL691455 | 0.78 | EGFR (0.78) | EGFRERBB2ERBB4 | |
| SCHEMBL28771965 | 0.74 | EGFR (0.82) | EGFRERBB2ERBB4 | |
| SCHEMBL18788863 | 0.73 | EGFR (0.61) | EGFRERBB2ERBB4 | |
| SCHEMBL3505411 | 0.72 | EGFR (0.62) | EGFRERBB2ERBB4 | |
| SCHEMBL17059600 | 0.71 | EGFR (0.74) | EGFR | |
| SCHEMBL1094554 | 0.71 | EGFR (0.81) | EGFRERBB2ERBB4 | |
| SCHEMBL691623 | 0.71 | EGFR (0.82) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015127873-A1 | ARYLAMINO PYRAMIDINE COMPOUND AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS PREPARED THEREFROM | 上海海雁医药科技有限公司 | 2015-09-03 | — | — | WO | disclosed |