Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.60 |
| ▸ | MAPK7 | Q13164 | 3/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059678 | 0.87 | MAPK7 (0.69) | BRD4MAPK7KCNH2LRRK2ALDH1A1 | |
| SCHEMBL18369941 | 0.87 | MAPK7 (0.77) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL17059748 | 0.86 | MAPK7 (0.61) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL17059937 | 0.84 | BRD4 (0.59) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL17059838 | 0.84 | MAPK7 (0.59) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369961 | 0.83 | MAPK7 (0.73) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18370006 | 0.81 | MAPK7 (0.89) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL17059780 | 0.81 | BRD4 (0.52) | BRD4MAPK7KCNH2LRRK2TP53 | |
| SCHEMBL18369949 | 0.80 | MAPK7 (0.74) | BRD4MAPK7KCNH2LRRK2DCLK1 | |
| SCHEMBL18369840 | 0.79 | BRD4 (0.84) | BRD4MAPK7KCNH2LRRK2DCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| WO-2015129927-A1 | HETEROCYCLIC COMPOUNDS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | BET1, EP300, RBBP5 | BRD4 4/4885MAPK7 58/4885KCNH2 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.