RBBP5

Retinoblastoma-binding protein 5 · Q15291 · RBBP5 on Sugi Atlas →

2,031 patent compounds predicted against RBBP5, 1,720 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL9940650 SCHEMBL9940650 0.43 5/20
SCHEMBL469241 SCHEMBL469241 0.76 4/20
SCHEMBL14706086 SCHEMBL14706086 0.76 4/20
SCHEMBL5184990 SCHEMBL5184990 0.56 4/20
SCHEMBL4561846 SCHEMBL4561846 0.48 4/20
SCHEMBL10252718 SCHEMBL10252718 0.47 4/20
SCHEMBL805652 SCHEMBL805652 0.69 3/20
SCHEMBL4727574 SCHEMBL4727574 0.54 3/20
SCHEMBL8463775 SCHEMBL8463775 0.54 3/20
SCHEMBL14905923 SCHEMBL14905923 0.54 3/20
SCHEMBL13976438 SCHEMBL13976438 0.52 3/20
SCHEMBL13978308 SCHEMBL13978308 0.52 3/20
SCHEMBL13986294 SCHEMBL13986294 0.51 3/20
SCHEMBL14454564 SCHEMBL14454564 0.51 3/20
SCHEMBL804176 SCHEMBL804176 0.50 3/20
SCHEMBL14905981 SCHEMBL14905981 0.50 3/20
SCHEMBL10249256 SCHEMBL10249256 0.45 3/20
SCHEMBL9106857 SCHEMBL9106857 0.44 3/20
SCHEMBL9940605 SCHEMBL9940605 0.43 3/20
SCHEMBL9105267 SCHEMBL9105267 0.43 3/20

Clinical trials — most relevant to RBBP5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt PHASE4COMPLETED
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision PHASE3COMPLETED
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor PHASE1/PHASE2NOT_YET_RECRUITING
Avelumab, Palbociclib and Axitinib in Advanced RCC PHASE2WITHDRAWN
Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers PHASE1/PHASE2COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
A Phase I Study of Systemic Gene Therapy With SGT-94 in Patients With Solid Tumors PHASE1COMPLETED
An Exploratory Biomarker Study of ARQ 501 in Patients With Advanced Solid Tumors PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma EARLY_PHASE1RECRUITING
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Genetic Analysis of Hereditary Prostate Cancer nanCOMPLETED
Cyclin-dependent Kinase Inhibitor 2A (Placental Senescence Marker) on Labor-related Signals nanUNKNOWN
Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients nanRECRUITING
Studying Health Outcomes After Treatment in Patients With Retinoblastoma nanRECRUITING
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
Profiles of Expression in HPV+ Versus HPV Head and Neck Cancers nanUNKNOWN
Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors nanENROLLING_BY_INVITATION
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization nanCOMPLETED
Retinoblastoma Biomarker Study nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Feasibility of Generating Pluripotent Stem Cells From Patients With Familial Retinoblastoma nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Molecular Analysis of Retinoblastoma nanCOMPLETED
Telomeres Length in Israeli Fibrotic ILD Patients nanENROLLING_BY_INVITATION
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a RBBP5 binder may also engage these)

ProteinNameSimilarity
Q8BX09 1.000 Q8BX09 →
Q9VPH8 0.998 Q9VPH8 →
Q3UMY5 0.997 Q3UMY5 →
Q09309 0.996 Q09309 →
Q09589 0.993 Q09589 →
Q652L2 0.993 Q652L2 →
O17468 0.993 O17468 →
Q6DIP5 0.992 Q6DIP5 →
Q2HJE1 0.992 Q2HJE1 →
Q8K3E5 0.992 Q8K3E5 →
Q6NL34 0.992 Q6NL34 →
Q6GM71 0.992 Q6GM71 →
Q7TMQ7 0.992 Q7TMQ7 →
Q9VKK2 0.991 Q9VKK2 →
Q84JM4 0.991 Q84JM4 →
F4IH25 0.991 F4IH25 →
Q9LXN4 0.991 Q9LXN4 →
A0A2R8QPS5 0.991 A0A2R8QPS5 →
Q5E915 0.991 Q5E915 →
WDR91 WD repeat-containing protein 91 0.991 landscape →
D3ZA12 0.991 D3ZA12 →
Q5R6T6 0.990 Q5R6T6 →
Q22006 0.990 Q22006 →
NFKB1 Nuclear factor NF-kappa-B p105 subunit 0.990 landscape →
Q6C710 0.990 Q6C710 →
A3KFM7 0.990 A3KFM7 →
Q5RE88 0.990 Q5RE88 →
Q6TEN6 0.990 Q6TEN6 →
KAT8 Histone acetyltransferase KAT8 0.990 landscape →
KDM5B Lysine-specific demethylase 5B 0.990 landscape →