Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17060705 | 0.93 | ADRB2 (0.66) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL17060706 | 0.92 | ADRB2 (0.59) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL14674013 | 0.92 | ADRB2 (0.59) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL17060698 | 0.87 | ADRB2 (0.65) | ADRB2ADRB1CHRM3 | |
| SCHEMBL14166422 | 0.87 | ADRB2 (0.65) | ADRB2ADRB1CHRM3 | |
| SCHEMBL14166602 | 0.87 | ADRB2 (0.65) | ADRB2ADRB1CHRM3 | |
| SCHEMBL14166297 | 0.87 | ADRB2 (0.65) | ADRB2ADRB1CHRM3 | |
| SCHEMBL17060701 | 0.87 | ADRB2 (0.65) | ADRB2ADRB1CHRM3 | |
| SCHEMBL14166186 | 0.87 | ADRB2 (0.65) | ADRB2ADRB1CHRM3 | |
| SCHEMBL14674012 | 0.85 | ADRB2 (0.60) | ADRB2ADRB1ADRB3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718281-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-09 | — | — | EP | claimed |