Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 9/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13471220 | 0.92 | SLC2A1 (0.47) | SLC2A1S1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL13279803 | 0.82 | S1PR1 (0.43) | SLC2A1S1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL13464647 | 0.81 | S1PR1 (0.39) | SLC2A1S1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL13464618 | 0.81 | S1PR1 (0.39) | SLC2A1S1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL13276050 | 0.80 | S1PR3 (0.69) | S1PR1S1PR3S1PR2LPAR2S1PR4 | |
| SCHEMBL13469236 | 0.78 | S1PR1 (0.40) | S1PR1S1PR3S1PR2LPAR2S1PR4 | |
| SCHEMBL13469327 | 0.78 | S1PR1 (0.40) | SLC2A1S1PR1S1PR3S1PR2LPAR2 | |
| SCHEMBL13469385 | 0.76 | S1PR1 (0.41) | S1PR1S1PR3S1PR2LPAR2S1PR4 | |
| SCHEMBL13275907 | 0.75 | RARB (0.49) | S1PR1S1PR3S1PR4S1PR5CTSV | |
| SCHEMBL2635388 | 0.74 | S1PR3 (0.45) | S1PR1S1PR3S1PR2LPAR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697212-B1 | PHENYL BICYCLIC METHYL AMINE DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS | ALLERGAN INC (US) | 2015-09-09 | — | — | EP | disclosed |