Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 13/20 | 0.45 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36206 | 0.84 | S1PR3 (0.66) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL14642670 | 0.77 | S1PR3 (0.46) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL17060880 | 0.74 | SLC2A1 (0.46) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL35846 | 0.74 | S1PR3 (0.67) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL15042602 | 0.73 | HDAC1 (0.36) | S1PR3S1PR1S1PR5 | |
| SCHEMBL36218 | 0.72 | S1PR3 (0.55) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL14642772 | 0.72 | S1PR3 (0.40) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL36337 | 0.70 | S1PR3 (0.87) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL36013 | 0.69 | S1PR3 (0.63) | S1PR3S1PR1S1PR2LPAR2S1PR4 | |
| SCHEMBL35848 | 0.69 | S1PR3 (0.63) | S1PR3S1PR1S1PR2LPAR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569322-A1 | AROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHONATE (S1P) RECEPTOR ACTIVITY | Allergan, Inc. (US) | 2013-03-20 | — | — | EP | claimed |
| WO-2011143332-A1 | AROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHONATE (S1P) RECEPTOR ACTIVITY | ALLERGAN, INC. (US) | 2011-11-17 | — | — | WO | claimed |