Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.62 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17164814 | 0.90 | PDE2A (0.54) | PDE2AAKT1AKT2MEN1KMT2A | |
| SCHEMBL8889645 | 0.90 | TSHR (0.55) | PDE2AAKT1AKT2MEN1KMT2A | |
| SCHEMBL11553859 | 0.90 | PDE2A (0.54) | PDE2AAKT1AKT2MEN1KMT2A | |
| SCHEMBL1409623 | 0.87 | TSHR (0.60) | PDE2AAKT1AKT2MEN1KMT2A | |
| SCHEMBL963755 | 0.87 | PDE2A (0.58) | PDE2ATSHRALDH1A1TAAR1KIF11 | |
| SCHEMBL95350 | 0.87 | MEN1 (0.59) | PDE2AAKT1AKT2MEN1KMT2A | |
| SCHEMBL529444 | 0.87 | PDE2A (0.52) | PDE2AAKT1AKT2MEN1KMT2A | |
| Iodide SCHEMBL25233686 | 0.85 | TSHR (0.57) | PDE2AAKT1AKT2MEN1KMT2A | |
| SCHEMBL5591445 | 0.85 | PDE2A (0.50) | PDE2AAKT1AKT2MEN1KMT2A | |
| SCHEMBL6135477 | 0.85 | PDE2A (0.50) | PDE2AAKT1AKT2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250376438-A1 | METHOD FOR PRODUCING ISOCYANATES VIA PHOSGENATION OF A MIXTURE OF (AR)ALIPHATIC DIAMINES AND CYCLOALIPHATIC DIAMINES | COVESTRO DEUTSCHLAND AG (DE) | 2025-12-11 | — | — | US | claimed |
| CN-118043022-A | Composition comprising a dye and an inorganic alkalizing agent | 花王株式会社 | 2024-05-14 | — | — | CN | claimed |
| EP-2658507-B1 | OXIDATIVE COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2019-04-24 | — | — | EP | claimed |
| EP-1598049-B1 | Composition for coloring of keratin fibres | KPSS KAO GMBH (DE) | 2008-08-06 | — | — | EP | claimed |
| EP-1250908-B1 | Hair dye | KPSS KAO GMBH (DE) | 2007-03-14 | — | — | EP | claimed |
| EP-1297818-A2 | Hair dye | KPSS-Kao Professional Salon Services GmbH (DE) | 2003-04-02 | — | — | EP | claimed |
| EP-1250908-A2 | Hair dye | GOLDWELL GmbH (DE) | 2002-10-23 | — | — | EP | claimed |
| US-4333730-A | HAIR DYES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-06-08 | — | — | US | claimed |
| US-4324553-A | OXIDATION COLOR DYES | L'OREAL (FR) | 1982-04-13 | — | — | US | claimed |
| US-20250376438-A1 | METHOD FOR PRODUCING ISOCYANATES VIA PHOSGENATION OF A MIXTURE OF (AR)ALIPHATIC DIAMINES AND CYCLOALIPHATIC DIAMINES | COVESTRO DEUTSCHLAND AG (DE) | 2025-12-11 | — | — | US | disclosed |
| EP-4543850-A1 | METHOD FOR PRODUCING ISOCYANTES VIA PHOSGENATION OF A MIXTURE OF (AR)ALIPHATIC DIAMINES AND CYCLOALIPHATIC DIAMINES | Covestro Deutschland AG (DE) | 2025-04-30 | — | — | EP | disclosed |
| CN-118043022-A | Composition comprising a dye and an inorganic alkalizing agent | 花王株式会社 | 2024-05-14 | — | — | CN | disclosed |
| US-11885694-B2 | Temperature sensor element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-01-30 | — | — | US | disclosed |
| WO-2023247522-A1 | METHOD FOR PRODUCING ISOCYANTES VIA PHOSGENATION OF A MIXTURE OF (AR)ALIPHATIC DIAMINES AND CYCLOALIPHATIC DIAMINES | COVESTRO DEUTSCHLAND AG (DE) | 2023-12-28 | — | — | WO | disclosed |
| EP-1250910-A1 | Hair dye composition | GOLDWELL GmbH (DE) | 2002-10-23 | — | — | EP | disclosed |
| US-4843160-A | Preparation of alpha-aminoalkylphenols | THE DOW CHEMICAL COMPANY (US) | 1989-06-27 | — | — | US | disclosed |
| US-4324553-A | OXIDATION COLOR DYES | L'OREAL (FR) | 1982-04-13 | — | — | US | disclosed |
| US-4253886-A | Corrosion resistant ferromagnetic metal powders and method of preparing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4137360-A | POLYURETHANE-POLYSILOXANE COPOLYMER | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-4086193-A | POLYURETHANE COAGULATED | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250376438-A1 | METHOD FOR PRODUCING ISOCYANATES VIA PHOSGENATION OF A MIXTURE OF (AR)ALIPHATIC DIAMINES AND CYCLOALIPHATIC DIAMINES | APEH, CDIPT, DDT | PDE2A 547/4885AKT1 2856/4885AKT2 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.