CDIPT

CDP-diacylglycerol--inositol 3-phosphatidyltransferase · O14735 · CDIPT on Sugi Atlas →

412 patent compounds predicted against CDIPT, 362 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4699731 SCHEMBL4699731 1.00 2/20
SCHEMBL16111548 SCHEMBL16111548 1.00 2/20
SCHEMBL29358745 SCHEMBL29358745 1.00 2/20
SCHEMBL29380618 SCHEMBL29380618 1.00 2/20
SCHEMBL29931136 SCHEMBL29931136 1.00 2/20
SCHEMBL4697866 SCHEMBL4697866 0.89 2/20
SCHEMBL24532075 SCHEMBL24532075 0.89 2/20
SCHEMBL4697696 SCHEMBL4697696 0.86 2/20
SCHEMBL23092285 SCHEMBL23092285 0.86 2/20
SCHEMBL29688472 SCHEMBL29688472 0.86 2/20
SCHEMBL22024695 SCHEMBL22024695 0.86 2/20
SCHEMBL16136600 SCHEMBL16136600 0.84 2/20
SCHEMBL24532058 SCHEMBL24532058 0.83 2/20
SCHEMBL4699947 SCHEMBL4699947 0.83 2/20
SCHEMBL22025026 SCHEMBL22025026 0.82 2/20
SCHEMBL22119546 SCHEMBL22119546 0.82 2/20
SCHEMBL24532062 SCHEMBL24532062 0.82 2/20
SCHEMBL18804561 SCHEMBL18804561 0.81 2/20
SCHEMBL22024561 SCHEMBL22024561 0.81 2/20
SCHEMBL22025030 SCHEMBL22025030 0.81 2/20

Clinical trials — most relevant to CDIPT by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
European Celecoxib Trial in Primary Breast Cancer PHASE3COMPLETED
Cytidine and Omega-3 Fatty Acids in Bipolar Disorder PHASE2COMPLETED
Lovaza's Effect on the Activation of Platelets PHASE2COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Phase I Clinical Trial of CDP1 in Patients With Advanced Solid Tumors PHASE1COMPLETED
Analysis of Tissues From Patients in Trial of Myo-Inositol to Prevent Lung Cancer PHASE1COMPLETED
CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer PHASE1RECRUITING
Liposomal Doxorubicin and PSC 833 in Treating Patients With AIDS-Related Kaposi's Sarcoma or Other Advanced Cancers PHASE1COMPLETED
Choline Effects - Pre-symptomatic AD PHASE1COMPLETED
Duality of Lipids: the Athlete's Paradox nanCOMPLETED
The Study Aims to Investigate the Effects of Oral Inositols on Insulin-resistance in Children With Obesity. nanUNKNOWN
Real-World Effectiveness of PLD in Platinum- Sensitive Recurrent Ovarian Cancer nanCOMPLETED
Free Fatty Acid Induced Insulin Resistance nanCOMPLETED
Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers nanCOMPLETED
Human Requirements for the Nutrient Choline nanCOMPLETED
Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver Failure nanCOMPLETED
Study of the Effect of a Nutritional Supplement on Microbiota, Metabolic Control, Inflammatory Profile, and Quality of Life in Patients With Polycystic Ovary Syndrome. nanRECRUITING
Investigation of Secreted Phosphoproteins and PiP3 (Phosphoinositolphospat 3) in Sputum nanCOMPLETED
Benefits of Eggs in Combination With a Plant-based Diet nanCOMPLETED
Choline to Improve Malnutrition and Enhance Cognition nanRECRUITING
Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome nanCOMPLETED
Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity. nanCOMPLETED
Lipidomic and Multi-Omics Profiling of Fatty Liver Disease in People With and Without HIV nanNOT_YET_RECRUITING
Whole Body Bone Scan vs 18F-Choline PET/CT in Prostate Cancer nanCOMPLETED
Oncometabolome and MALDI-MSI in Upper GI Carcinomas - Chemosensitivity in Esophageal Carcinoma nanACTIVE_NOT_RECRUITING
Precision Medicine for Sng/Pain Control nanCOMPLETED
Myoinositol Treatment and Asprosin Levels in PCOS nanCOMPLETED
Choline PET/CT vs. MeAIB PET/CT in Prostate Cancer nanWITHDRAWN
Partial PTEN Deletion in Breast Cancer nanUNKNOWN
Phospholipid-rich Dairy Extract for Cognitive Function nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a CDIPT binder may also engage these)

ProteinNameSimilarity
P70500 1.000 P70500 →
Q8VDP6 1.000 Q8VDP6 →
Q8SX37 0.994 Q8SX37 →
Q10153 0.991 Q10153 →
P06197 0.988 P06197 →
Q59RA2 0.987 Q59RA2 →
Q8GUK6 0.981 Q8GUK6 →
Q8LBA6 0.979 Q8LBA6 →
O82568 0.971 O82568 →
Q9HXE9 0.970 Q9HXE9 →
O13901 0.970 O13901 →
P70245 0.967 P70245 →
P22140 0.967 P22140 →
O82567 0.966 O82567 →
P17898 0.966 P17898 →
Q9EQY6 0.966 Q9EQY6 →
Q7ZW02 0.966 Q7ZW02 →
Q8C2R7 0.965 Q8C2R7 →
O01916 0.965 O01916 →
P53439 0.965 P53439 →
Q9Y123 0.965 Q9Y123 →
Q0VCC1 0.965 Q0VCC1 →
Q2U6A4 0.965 Q2U6A4 →
J7FIJ6 0.965 J7FIJ6 →
Q9LJK3 0.964 Q9LJK3 →
O04928 0.964 O04928 →
A9CIM3 0.963 A9CIM3 →
O80505 0.963 O80505 →
Q6BZW3 0.963 Q6BZW3 →
Q8N2M4 0.963 Q8N2M4 →