SCHEMBL170616

SCHEMBL170616

N#Cc1cnn2c(=O)cc[nH]c12

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4D Q6B0I6 2/20 0.40
PLAT P00750 3/20 0.40
MCL1 Q07820 1/20 0.37
CSNK2A1 P68400 4/20 0.35
KDM5A P29375 2/20 0.35
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 4/20 0.34
HPGD P15428 2/20 0.34
CLK4 Q9HAZ1 1/20 0.34
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
XDH P47989 1/20 0.33
MEN1 O00255 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4C Q9H3R0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31710635 0.74 PLAT (0.36) PLATALDH1A1
SCHEMBL13153943 0.74 KDM4E (0.31) KDM4E
SCHEMBL30781520 0.74 AURKA (0.31)
SCHEMBL16077836 0.71 PLAT (0.47) KDM4DPLATKDM5AKDM4EALDH1A1
SCHEMBL6642824 0.71 KDM4E (0.48) KDM4DCSNK2A1KDM5AKDM4EALDH1A1
SCHEMBL12953361 0.69 KDM4E (0.43) KDM4DPLATCSNK2A1KDM4EALDH1A1
SCHEMBL16050813 0.69 KDM5A (0.46) KDM4DPLATKDM5AKDM4EALDH1A1
SCHEMBL3788643 0.69 PLAT (0.43) PLATKDM4EALDH1A1HPGDCLK4
SCHEMBL9299371 0.68 CDK2 (0.43) KDM4DPLATKDM4EALDH1A1KMT2A
SCHEMBL16046503 0.68 PLAT (0.44) KDM4DPLATKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2054021-B1 HAIR DYE COMPRISING RICE GERM OIL AND PROTEIN HYDROLYZATE HENKEL AG & CO KGAA (DE) 2017-10-18 EP disclosed
EP-1815839-B1 Hair colouring method HENKEL AG & CO KGAA (DE) 2017-06-21 EP disclosed
EP-2211994-B1 OXIDATIVE DYEING METHOD FOR KERATINOUS FIBERS HENKEL AG & CO KGAA (DE) 2017-01-04 EP disclosed
EP-2178492-B1 HAIR TREATMENT AGENT COMPRISING AN ACYLAMINO ACID DERIVATIVE, A HYDROXYALKYLAMINE, AND 2-(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE HENKEL AG & CO KGAA (DE) 2016-12-14 EP disclosed
EP-2558190-B1 PROCESS FOR PREPARING A COLOURING COMPOSITION FOR KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2016-07-06 EP disclosed
EP-2970307-A1 PYRAZOLO COMPOUNDS AND USES THEREOF Genentech, Inc. (US) 2016-01-20 EP disclosed
WO-2015135094-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2015-09-17 WO disclosed
WO-2014139326-A1 PYRAZOLO COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2014-09-18 WO disclosed
EP-1789015-B1 METHOD FOR STYLISHLY CHANGING THE COLOR OF KERATINIC FIBERS HENKEL AG & CO KGAA (DE) 2014-04-23 EP disclosed
EP-1771145-B1 Agents for the simultaneous dyeing and bleaching of keratin-containing fibers HENKEL AG & CO KGAA (DE) 2012-11-21 EP disclosed
WO-2007025750-A1 AGENTS FOR THE TREATMENT OF KERATIN FIBRES CONTAINING NANOSCALE CALCIUM SALTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-08 WO disclosed
EP-1759735-A1 Method of selectively dyeing portions of hair Henkel Kommanditgesellschaft auf Aktien (DE) 2007-03-07 EP disclosed
EP-1292272-B1 OXIDATION DYE FOR HAIR HENKEL KGAA (DE) 2007-03-07 EP disclosed
WO-2007019930-A1 AGENT FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-02-22 WO disclosed
WO-2007019931-A1 AGENT FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-02-22 WO disclosed
WO-2007017048-A1 METHOD FOR QUICKLY CONCEALING THE ROOTS OF HAIR THAT HAVE GROWN AFTER THE HAIR HAS BEEN DYED HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-02-15 WO disclosed
EP-1752138-A2 Amaranth seed oil in hair compositions Henkel Kommanditgesellschaft auf Aktien (DE) 2007-02-14 EP disclosed
EP-1752191-A1 Agent for bleaching and/or colouring keratinic fibres with a coated alkaline agent Henkel Kommanditgesellschaft auf Aktien (DE) 2007-02-14 EP disclosed
WO-2007009530-A1 HAIR-TREATMENT KIT COMPRISING A DYE AND AN ADHESIVE STRIP AS A DYE-PROTECTION MEANS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-25 WO disclosed
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO disclosed