SCHEMBL1706162

SCHEMBL1706162

CCOC(Cc1ccc(N)cc1)C(=O)OC(=O)C(Cc1cccc(N)c1)OCC

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.42
PPARA Q07869 17/20 0.42
PPARG P37231 15/20 0.42
PPARD Q03181 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1706161 0.88 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL4081032 0.87 PPARG (0.44) PPARAPPARGPPARD
SCHEMBL1861279 0.85 PPARG (0.44) PPARAPPARGPPARD
SCHEMBL756254 0.82 PPARG (0.57) PPARAPPARGPPARD
SCHEMBL4075927 0.81 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL13649255 0.81 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL1856323 0.81 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL1865433 0.79 PPARA (0.48) PPARAPPARGPPARD
SCHEMBL14477219 0.79 PPARG (0.45) PPARAPPARGPPARD
SCHEMBL1104874 0.77 PPARG (0.43) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2131829-B1 PPAR-gamma agonists for the induction of cationic antimicrobial peptide expression as immunoprotective stimulants GIULIANI INT LTD (IE) 2012-04-18 EP disclosed