Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 3/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17062967 | 1.00 | TSHR (0.38) | TSHRSMN1; SMN2ALDH1A1CYP19A1MAPT | |
| SCHEMBL5571445 | 0.83 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1CYP19A1MAPT | |
| SCHEMBL17062991 | 0.82 | TRPV1 (0.55) | TSHRALDH1A1CYP19A1MAPTPPARG | |
| SCHEMBL17062993 | 0.82 | TRPV1 (0.55) | TSHRALDH1A1CYP19A1MAPTPPARG | |
| SCHEMBL18578734 | 0.77 | TSHR (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL18578735 | 0.77 | TSHR (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL17062934 | 0.74 | FAAH (0.50) | TSHRSMN1; SMN2ALDH1A1CYP19A1MAPT | |
| SCHEMBL17062936 | 0.74 | FAAH (0.50) | TSHRSMN1; SMN2ALDH1A1CYP19A1MAPT | |
| SCHEMBL5134464 | 0.73 | — | — | |
| SCHEMBL17063006 | 0.73 | FAAH (0.53) | TSHRSMN1; SMN2CYP19A1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738853-B2 | Renewably derived aldehydes and methods of making and using the same | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20150252290-A1 | Renewably Derived Aldehydes and Methods of Making and Using the Same | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2015-09-10 | — | — | US | disclosed |