⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200409 | 0.70 | — | — | |
| SCHEMBL712303 | 0.65 | — | — | |
| SCHEMBL325170 | 0.63 | — | — | |
| SCHEMBL7649949 | 0.63 | — | — | |
| Bicarbonate SCHEMBL2491825 | 0.60 | — | — | |
| SCHEMBL1503487 | 0.60 | — | — | |
| SCHEMBL1022318 | 0.60 | — | — | |
| SCHEMBL316938 | 0.60 | — | — | |
| SCHEMBL3676073 | 0.60 | — | — | |
| SCHEMBL2414 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431610-B2 | Alkanoylamino benzamide aniline HDAC inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120301426-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| US-8258316-B2 | Alkanoylamino benzamide aniline HDAC inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| CN-102459159-A | Alkanoylamino benzamide aniline hdac inihibitor compounds | GILEAD COLORADO INC | 2012-05-16 | — | — | CN | disclosed |
| EP-2440519-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144371-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | GILEAD COLORADO, INC. (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100310500-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| EP-1140958-B1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RES & DEV (IL) | 2006-03-15 | — | — | EP | disclosed |
| US-6642365-B1 | Kanamycin, gentamycin or neomycin bonded to arginine; use for treatment of HIV infections and AIDS (acquired immune deficiency disease) | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-11-04 | — | — | US | disclosed |
| EP-1140958-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039139-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-07-06 | — | — | WO | disclosed |