⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912677 | 0.74 | — | — | |
| SCHEMBL26854555 | 0.74 | — | — | |
| SCHEMBL19546490 | 0.74 | — | — | |
| SCHEMBL26854627 | 0.74 | — | — | |
| SCHEMBL25616363 | 0.72 | — | — | |
| SCHEMBL28143590 | 0.70 | — | — | |
| SCHEMBL7648237 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL25645500 | 0.67 | — | — | |
| SCHEMBL25752683 | 0.67 | — | — | |
| SCHEMBL14904897 | 0.65 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113763-A1 | SOLID PRODRUG FORMS OF 2'-CHLORO-2'-METHYL URIDINE FOR HCV | Idenix Pharmaceuticals LLC (US) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134780-A1 | SOLID PRODRUG FORMS OF 2'-CHLORO-2'-METHYL URIDINE FOR HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2015-09-11 | — | — | WO | disclosed |