Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065132 | 0.75 | CYP19A1 (0.39) | CYP19A1LMNACFTRGOPCP2RX1 | |
| SCHEMBL13297792 | 0.73 | CYP19A1 (0.38) | CYP19A1LMNACFTRGOPCP2RX1 | |
| SCHEMBL13297786 | 0.73 | CYP19A1 (0.38) | CYP19A1LMNACFTRGOPCP2RX1 | |
| SCHEMBL13297824 | 0.72 | CYP19A1 (0.38) | CYP19A1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL13297806 | 0.72 | CYP19A1 (0.41) | CYP19A1LMNAP2RX1P2RX3P2RX4 | |
| SCHEMBL13297795 | 0.70 | RXFP1 (0.45) | CYP19A1LMNAALDH1A1RXFP1BACE1 | |
| SCHEMBL13297828 | 0.69 | CYP19A1 (0.39) | CYP19A1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL13297805 | 0.69 | GRIN2B (0.45) | CYP19A1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL13297833 | 0.69 | CYP19A1 (0.39) | CYP19A1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL11470019 | 0.69 | CYP19A1 (0.84) | CYP19A1LMNAALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-19 | — | — | US | disclosed |
| EP-3114150-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134591-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2015-09-11 | — | — | WO | disclosed |
| US-8980824-B2 | Tubulysin compounds, methods of making and use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| CN-1430605-A | Method for synthesizing amine ethers from secondary amino oxides | CIBA SC HOLDING AG (CH) | 2003-07-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | GLO1, TET1, RIOX2 | CYP19A1 581/4885LMNA 3944/4885CFTR 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.