Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544438 | 1.00 | KDR (0.59) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL31544442 | 1.00 | KDR (0.59) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL31544439 | 1.00 | KDR (0.59) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL5051826 | 0.87 | KDR (0.68) | KDRCHEK1RAB9AKDM4EMAPT | |
| Methane SCHEMBL28704887 | 0.85 | KDR (0.66) | KDRCHEK1RAB9AKDM4EMAPT | |
| Benzene SCHEMBL27629233 | 0.85 | RAB9A (0.69) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL27927203 | 0.83 | MAPT (0.50) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL10176240 | 0.82 | KDR (0.61) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL17065800 | 0.80 | MEN1 (0.63) | KDRCHEK1RAB9AKDM4EMAPT | |
| SCHEMBL27927108 | 0.80 | FFAR1 (0.53) | RAB9AKDM4EMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445989-B | Phosphine ligand with indole skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2020-05-29 | — | — | CN | claimed |
| CN-104945434-A | (2-disubstituted phosphino-phenyl)-1-alkyl-indol-phosphine ligand and synthetic method and application thereof | SHENZHEN RES INST THE HONG KONG POLYTECHNIC UNIVERSITY | 2015-09-30 | — | — | CN | claimed |
| CN-101935297-B | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2012-09-05 | — | — | CN | claimed |
| CN-101935297-A | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2011-01-05 | — | — | CN | claimed |
| CN-111825686-A | Oxazepino [3,2-b ] indole compound and synthetic method thereof | 贵州医科大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-107445989-B | Phosphine ligand with indole skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2020-05-29 | — | — | CN | disclosed |
| CN-109438451-A | The method of level-one amine guiding building 6- (2- bromophenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-104945434-B | (2 ﹣ bis- substitution phosphines phenyl) -1- alkyl-indols Phosphine ligands and its synthetic method and application | 香港理工大学深圳研究院 | 2018-05-18 | — | — | CN | disclosed |
| CN-107445989-A | A kind of Phosphine ligands of indoles skeleton and its preparation method and application | 香港理工大学深圳研究院 | 2017-12-08 | — | — | CN | disclosed |
| CN-104892614-B | A kind of synthetic method of 6H iso-indoles simultaneously ketone derivatives of [2,1 α] indoles 6 | 福建师范大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-104945434-A | (2-disubstituted phosphino-phenyl)-1-alkyl-indol-phosphine ligand and synthetic method and application thereof | SHENZHEN RES INST THE HONG KONG POLYTECHNIC UNIVERSITY | 2015-09-30 | — | — | CN | disclosed |
| WO-2015133804-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 두산 | 2015-09-11 | — | — | WO | disclosed |
| CN-104892614-A | Synthesis method of 6H-isoindolo[2, 1-alpha]indol-6-one derivative | UNIV FUJIAN | 2015-09-09 | — | — | CN | disclosed |
| CN-103145710-B | The synthetic method of indole-imidazole compound | BEIJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-103145710-A | Synthesis method of indole-imidazole compound | UNIV BEIJING TECHNOLOGY | 2013-06-12 | — | — | CN | disclosed |
| CN-101935297-B | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2012-09-05 | — | — | CN | disclosed |
| CN-101935297-A | 3,3- diindolyl derivative and preparation method thereof | UNIV ZHEJIANG | 2011-01-05 | — | — | CN | disclosed |