Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9227752 | 0.98 | POLB (0.49) | MAPTPOLBTDP1L3MBTL1NR4A2 | |
| SCHEMBL9861538 | 0.95 | POLB (0.49) | MAPTPOLBTDP1L3MBTL1NR4A2 | |
| SCHEMBL24983640 | 0.90 | NR4A2 (0.49) | NR4A2NR4A1NR4A3THRATHRB | |
| SCHEMBL9227742 | 0.87 | GLRA1 (0.50) | MAPTPOLBTDP1L3MBTL1NR4A2 | |
| SCHEMBL31644500 | 0.87 | MAOB (0.51) | MAPTPOLBTDP1L3MBTL1LMNA | |
| SCHEMBL31644614 | 0.84 | LMNA (0.58) | MAPTPOLBTDP1MEN1KMT2A | |
| SCHEMBL24983834 | 0.83 | KCNA3 (0.47) | POLBNR4A2NR4A1NR4A3THRA | |
| SCHEMBL12694517 | 0.81 | MCL1 (0.43) | MAPTPOLBTDP1L3MBTL1NR4A2 | |
| SCHEMBL12692636 | 0.81 | POLB (0.40) | MAPTPOLBTDP1L3MBTL1NR4A2 | |
| SCHEMBL31643752 | 0.80 | PTPN1 (0.47) | MAPTPOLBTDP1L3MBTL1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170473-B | With asymmetry difunctional bending nuclear reactivity mesomorphic and its preparation method | 东进世美肯株式会社 | 2018-03-16 | — | — | CN | disclosed |
| CN-106170473-A | Have asymmetry difunctional bending nuclear reactivity mesomorphic and preparation method | 东进世美肯株式会社 | 2016-11-30 | — | — | CN | disclosed |
| WO-2015133872-A1 | BENT-CORE REACTIVE MESOGEN WITH ASYMMETRIC BIFUNCTIONAL GROUP AND METHOD FOR PREPARING SAME | 금오공과대학교 산학협력단 | 2015-09-11 | — | — | WO | disclosed |