Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 9/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619188 | 0.85 | ALDH1A1 (0.47) | SCN10AKCNH2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17066290 | 0.76 | SCN10A (0.53) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL15007948 | 0.74 | SCN10A (0.54) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL5949923 | 0.74 | SCN10A (0.54) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL17066708 | 0.72 | CYP2A6 (0.43) | ALDH1A1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL12549011 | 0.72 | SCN10A (0.76) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL1690431 | 0.72 | SCN2A (0.55) | SCN10AKCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL846855 | 0.71 | SCN10A (0.58) | SCN10AKCNH2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10005347 | 0.71 | ALDH1A1 (0.46) | SCN10AKCNH2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18506235 | 0.70 | SCN10A (0.54) | SCN10AKCNH2SCN1ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125904-B1 | Biphenyl imidazoles and related compounds useful for treating HCV infections | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-08 | — | — | US | disclosed |