Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083722 | 0.88 | HIF1A (0.69) | PRKAA2RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL1433245 | 0.88 | POLB (0.58) | ALDH1A1FAAHKMT2AHTTLMNA | |
| SCHEMBL24670268 | 0.84 | KMT2A (0.64) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL2451687 | 0.84 | KMT2A (0.64) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL29101948 | 0.83 | POLB (0.53) | ALDH1A1FAAHTNIKKMT2AHTT | |
| SCHEMBL17054969 | 0.83 | NPC1 (0.72) | NPC1TNFNOD2NOD1PRKAA2 | |
| SCHEMBL377536 | 0.81 | VEGFA (0.53) | NPC1RAB9AMAPTALDH1A1FAAH | |
| SCHEMBL13594993 | 0.80 | LCK (0.52) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL18083682 | 0.80 | HIF1A (0.58) | PRKAA2MAPTKDM4EALDH1A1FAAH | |
| SCHEMBL18083773 | 0.80 | MAPT (0.65) | NPC1RAB9AMAPTKDM4EFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125904-B1 | Biphenyl imidazoles and related compounds useful for treating HCV infections | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-9125904-B1 | Biphenyl imidazoles and related compounds useful for treating HCV infections | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-08 | — | — | US | disclosed |