Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066443 | 0.87 | HTR2A (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6TP53 | |
| SCHEMBL17066444 | 0.76 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL18237562 | 0.72 | HTR2A (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6TP53 | |
| SCHEMBL18250388 | 0.71 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3CACNB4CACNA1A | |
| SCHEMBL17055179 | 0.70 | CACNB4 (0.40) | TP53CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL17066197 | 0.69 | HTR2C (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL18250382 | 0.69 | HTR2A (0.35) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL28642004 | 0.68 | HTR2A (0.54) | MEN1GMNNLMNAMAPTPMP22 | |
| SCHEMBL18237855 | 0.67 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL6326457 | 0.66 | SMN1; SMN2 (0.41) | SLC6A2SLC6A4SLC6A3CACNB4CACNA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125866-B1 | Antidepressant compounds | KING SAUD UNIVERSITY (SA) | 2015-09-08 | — | — | US | disclosed |