Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066197 | 0.88 | HTR2C (0.39) | SLC6A4SLC6A2CYP2D6HTR2CSLC6A3 | |
| SCHEMBL18237855 | 0.88 | SLC6A4 (0.43) | SLC6A4SLC6A2CYP2D6HTR2CSLC6A3 | |
| SCHEMBL18237562 | 0.83 | HTR2A (0.40) | SLC6A4SLC6A2CYP2D6HTR2CSLC6A3 | |
| SCHEMBL18250388 | 0.80 | HTR2A (0.37) | SLC6A4SLC6A2HTR2CSLC6A3HTR2A | |
| SCHEMBL18250382 | 0.78 | HTR2A (0.35) | CYP2D6HTR2CCYP2C19CYP3A4HTR2A | |
| SCHEMBL17066441 | 0.76 | SLC6A2 (0.37) | SLC6A4SLC6A2CYP2D6SLC6A3CYP2C19 | |
| SCHEMBL18237561 | 0.75 | HTR2A (0.35) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL17066445 | 0.74 | SLC6A4 (0.44) | SLC6A4SLC6A2CYP2D6HTR2CSLC6A3 | |
| SCHEMBL18237481 | 0.74 | CACNB4 (0.35) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL18237417 | 0.70 | NLRP3 (0.39) | CYP2D6SLC6A3CYP2C19CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9498460-B1 | Halogenated tetracyclic compounds | KING SAUD UNIVERSITY (SA) | 2016-11-22 | — | — | US | disclosed |
| US-9498460-B1 | Halogenated tetracyclic compounds | KING SAUD UNIVERSITY (SA) | 2016-11-22 | — | — | US | disclosed |
| US-9125866-B1 | Antidepressant compounds | KING SAUD UNIVERSITY (SA) | 2015-09-08 | — | — | US | disclosed |