SCHEMBL17066487

SCHEMBL17066487

C=C/C=C(\C=C/C)/C=C/c1ccc(O)c(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.61
CYP2D6 P10635 3/20 0.57
NFE2L2 Q16236 3/20 0.57
ALOX5 P09917 3/20 0.57
CYP1A2 P05177 2/20 0.57
NFKB1 P19838 2/20 0.57
HSD11B1 P28845 2/20 0.57
STAT3 P40763 2/20 0.57
NFKB2 Q00653 2/20 0.57
RELA Q04206 2/20 0.57
APP P05067 3/20 0.56
KDM4E B2RXH2 2/20 0.56
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA3 P07451 2/20 0.56
PKM P14618 2/20 0.56
CA4 P22748 2/20 0.56
CA6 P23280 2/20 0.56
CA5A P35218 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17936382 0.89 KDM4E (0.54) CYP2D6NFE2L2CYP1A2KDM4ECA1
SCHEMBL14986903 0.81 MAPT (0.54) APPKDM4EMAPTALDH1A1LMNA
Isoeugenol SCHEMBL21489551 0.79 TYR (0.90) TYRCYP2D6NFE2L2ALOX5CYP1A2
Cis/Trans-Isoeugenol SCHEMBL29361918 0.77 TYR (1.00) TYRCYP2D6NFE2L2ALOX5CYP1A2
Isoeugenol SCHEMBL300766 0.77 TYR (1.00) TYRCYP2D6NFE2L2ALOX5CYP1A2
Cis/Trans-Isoeugenol SCHEMBL2463283 0.77 TYR (1.00) TYRCYP2D6NFE2L2ALOX5CYP1A2
Isoeugenol SCHEMBL29369838 0.77 TYR (1.00) TYRCYP2D6NFE2L2ALOX5CYP1A2
Isoeugenol SCHEMBL2463281 0.77 TYR (1.00) TYRCYP2D6NFE2L2ALOX5CYP1A2
Cis/Trans-Isoeugenol SCHEMBL57987 0.77 TYR (1.00) TYRCYP2D6NFE2L2ALOX5CYP1A2
Isoeugenol SCHEMBL57986 0.77 TYR (1.00) TYRCYP2D6NFE2L2ALOX5CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9125973-B2 Antimicrobial housing and cover for a medical device BAXTER INTERNATIONAL INC. (US) 2015-09-08 US disclosed