Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | FDPS | P14324 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17936382 | 0.89 | KDM4E (0.54) | ALDH1A1HPGDSMN1; SMN2MAPK1KDM4E | |
| SCHEMBL17066487 | 0.81 | TYR (0.61) | MAPTALDH1A1HPGDLMNAHTT | |
| SCHEMBL13168868 | 0.76 | KDM4E (0.82) | ALDH1A1HPGDFDPSSMN1; SMN2ACHE | |
| SCHEMBL13168869 | 0.76 | KDM4E (0.82) | ALDH1A1HPGDFDPSSMN1; SMN2ACHE | |
| SCHEMBL9722092 | 0.74 | ALDH1A1 (0.78) | MAPTALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL6026535 | 0.73 | KDM4E (0.73) | ALDH1A1HPGDFDPSSMN1; SMN2ACHE | |
| SCHEMBL6026533 | 0.73 | KDM4E (0.73) | ALDH1A1HPGDFDPSSMN1; SMN2ACHE | |
| SCHEMBL30360542 | 0.73 | KDM4E (0.68) | FDPSACHEAPPKDM4EBCHE | |
| SCHEMBL30360544 | 0.73 | KDM4E (0.68) | FDPSACHEAPPKDM4EBCHE | |
| SCHEMBL30257339 | 0.73 | KDM4E (0.68) | FDPSACHEAPPKDM4EBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | CRYAA, CRYAB, HSPH1 | MAPT 17/4885ALDH1A1 2438/4885HPGD 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.