Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453769 | 0.90 | ALDH1A1 (0.70) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13454451 | 0.90 | ALDH1A1 (0.70) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13454712 | 0.89 | ALDH1A1 (0.69) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13454758 | 0.89 | ALDH1A1 (0.69) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13454721 | 0.89 | ALDH1A1 (0.69) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13454373 | 0.89 | KMT2A (0.69) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL17066664 | 0.89 | ALDH1A1 (0.65) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13454547 | 0.88 | ALDH1A1 (0.68) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13470048 | 0.87 | ALDH1A1 (0.67) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL13454764 | 0.87 | ALDH1A1 (0.74) | KMT2AALDH1A1MEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |