SCHEMBL17067306

SCHEMBL17067306

CC1(C)CC(NC(=O)c2ccc(Cl)cc2Cl)CC(C)(C)N1

nearest known ligand 0.81

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.64
MEN1 O00255 2/20 0.64
MAPK1 P28482 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HSD17B10 Q99714 1/20 0.59
EZH2 Q15910 3/20 0.58
POLB P06746 1/20 0.53
GLA P06280 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8739254 0.81 EZH2 (0.72) KMT2AMEN1EZH2
SCHEMBL17067286 0.80 MEN1 (0.71) KMT2AMEN1MAPK1SMN1; SMN2EZH2
SCHEMBL29077678 0.79 HPGD (0.71) SMN1; SMN2POLBL3MBTL1
SCHEMBL4702446 0.78 PYGL (0.67) KMT2AMEN1EZH2
SCHEMBL8504043 0.78 KMT2A (0.76) KMT2AMEN1HSD17B10EZH2POLB
SCHEMBL6516959 0.78 PYGL (0.66) KMT2AMEN1EZH2
SCHEMBL6121489 0.75 HSD17B10 (0.64) KMT2AMEN1MAPK1HSD17B10EZH2
SCHEMBL6120920 0.75 MEN1 (0.77) KMT2AMEN1EZH2POLBGLA
SCHEMBL169747 0.75 EZH2 (0.80) KMT2AMEN1EZH2POLBGLA
SCHEMBL20968343 0.74 HSD17B10 (0.60) KMT2AMEN1HSD17B10EZH2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170298224-A1 Oxygen Scavenging Composition for Plastic Material CLARIANT INTERNATIONAL LTD. (CH) 2017-10-19 US disclosed
US-20170298224-A1 Oxygen Scavenging Composition for Plastic Material CLARIANT INTERNATIONAL LTD. (CH) 2017-10-19 US disclosed
WO-2015135635-A1 OXYGEN SCAVENGING COMPOSITION FOR PLASTIC MATERIAL CLARIANT INTERNATIONAL LTD (CH) 2015-09-17 WO disclosed
EP-2915842-A1 Oxygen scavenging composition for plastic material Clariant International Ltd. (CH) 2015-09-09 EP disclosed