Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 5/20 | 0.64 |
| ▸ | RECQL | P46063 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.55 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.55 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.55 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.55 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903174 | 0.86 | CD40 (0.48) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL14557795 | 0.86 | TIMP3 (0.71) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL375680 | 0.85 | TIMP3 (0.75) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL18211300 | 0.84 | TIMP3 (0.60) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL18211299 | 0.84 | TIMP3 (0.54) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL18211298 | 0.84 | TIMP3 (0.64) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL18136599 | 0.81 | TIMP3 (0.93) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11593603 | 0.80 | TIMP3 (0.68) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL3295536 | 0.80 | P2RY11 (0.68) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL3300014 | 0.80 | HSD17B10 (0.74) | TIMP3RECQLKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486497-B2 | Treatment of immunocompromised conditions | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-11-08 | — | — | US | disclosed |
| EP-2915539-A1 | Treatment of immunocompromised conditions with E-Selectin antagonist and G-CSF | Mater Medical Research Institute (AU) | 2015-09-09 | — | — | EP | disclosed |