Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 15/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362515 | 0.83 | SLC22A12 (0.40) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL5524129 | 0.83 | SLC22A12 (0.40) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL3418015 | 0.83 | SLC22A12 (0.47) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL23022609 | 0.82 | SLC22A12 (0.43) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19867947 | 0.75 | SLC22A12 (0.41) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19867938 | 0.75 | SLC22A12 (0.48) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL17069750 | 0.75 | SLC22A12 (0.53) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL10176706 | 0.74 | SLC22A12 (0.67) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL27951684 | 0.74 | SLC22A12 (0.43) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL15605855 | 0.73 | SLC22A12 (0.49) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150252010-A1 | MANUFACTURE OF 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID | ARDEA BIOSCIENCES, INC. | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252010-A1 | MANUFACTURE OF 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID | CYP1B1, ABAT, ALDH18A1 | SLC22A12 3336/4885CYP2C9 51/4885CYP2C19 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.