Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 5/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 6/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070230 | 0.95 | ESR2 (0.34) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL17070248 | 0.93 | CYP2C9 (0.37) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL17070241 | 0.93 | ESR2 (0.32) | ESR2 | |
| SCHEMBL17070227 | 0.92 | ESR2 (0.34) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL16257997 | 0.91 | CYP2C9 (0.33) | CYP2C9SPHK1MAPTGAAALDH1A1 | |
| SCHEMBL12625971 | 0.91 | P2RY14 (0.33) | CYP2C9CYP3A4P2RY14DGAT1 | |
| SCHEMBL17070246 | 0.90 | ESR2 (0.34) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL17070265 | 0.89 | CYP3A4 (0.34) | ESR2CYP2C9CYP3A4 | |
| SCHEMBL13002553 | 0.89 | CYP2C9 (0.40) | ESR2CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL12626245 | 0.89 | CYP2C9 (0.31) | CYP2C9MAPTGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493704-B2 | Cycloheptane derivative and preparation method and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-11-15 | — | — | US | disclosed |
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252261-A1 | CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | DHPS, DHCR24, CCNT1 | ESR2 3520/4885CYP2C9 1304/4885ESR1 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.