Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070436 | 0.96 | THRB (0.36) | THRBTHRAS1PR1S1PR3TNNC1 | |
| SCHEMBL17070406 | 0.90 | THRB (0.37) | THRBTHRAS1PR1S1PR3TNNC1 | |
| SCHEMBL21787295 | 0.90 | RARB (0.37) | THRBTHRAS1PR1S1PR3TNNC1 | |
| SCHEMBL17070387 | 0.89 | HTT (0.35) | THRBTHRAS1PR1S1PR3TNNC1 | |
| SCHEMBL17070392 | 0.88 | THRB (0.41) | THRBTHRARARBPPARGPPARA | |
| SCHEMBL17070434 | 0.88 | THRB (0.36) | THRBTHRAS1PR1S1PR3TNNC1 | |
| SCHEMBL17070470 | 0.87 | THRB (0.40) | THRBTHRARARBPPARGPPARA | |
| SCHEMBL17070441 | 0.87 | THRB (0.40) | THRBTHRARARBPPARGPPARA | |
| SCHEMBL17070433 | 0.87 | THRB (0.40) | THRBTHRARARBPPARGPPARA | |
| SCHEMBL17070377 | 0.86 | RARB (0.36) | THRBTHRAS1PR1S1PR3TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730590-A1 | LIQUID CRYSTAL MEDIA WITH HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-2918658-B1 | Liquid crystalline media with homeotropic alignment | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| US-10513657-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-12-24 | — | — | US | disclosed |
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| EP-2918658-A2 | Liquid crystalline media with homeotropic alignment | Merck Patent GmbH (DE) | 2015-09-16 | — | — | EP | disclosed |
| US-20150252265-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20150252265-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2015-09-10 | — | — | US | disclosed |