SCHEMBL17070403

SCHEMBL17070403

C=C(C)C(=O)OCCCc1ccc(-c2ccc(-c3ccc(OCCO)c(CCOC(=O)C(=C)C)c3)c(CC)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.40
RARG P13631 7/20 0.40
RARA P10276 6/20 0.40
CNR2 P34972 2/20 0.36
CNR1 P21554 1/20 0.36
PDE4A P27815 2/20 0.35
PDE4B Q07343 2/20 0.35
PDE4C Q08493 2/20 0.35
PDE4D Q08499 2/20 0.35
MTNR1B P49286 1/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
TSHR P16473 2/20 0.33
PTPN1 P18031 1/20 0.33
PTPN6 P29350 1/20 0.33
PTPN11 Q06124 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31746991 0.94 RARB (0.39) RARBRARGRARACNR2CNR1
SCHEMBL17063573 0.94 RARB (0.39) RARBRARGRARACNR2CNR1
SCHEMBL17070497 0.94 HTT (0.40) RARBRARGRARACNR2CNR1
SCHEMBL17070418 0.93 PDE4A (0.39) RARBRARGRARACNR2CNR1
SCHEMBL17070363 0.91 CNR2 (0.39) RARBRARGRARACNR2CNR1
SCHEMBL17070415 0.91 CNR2 (0.36) RARBRARGRARACNR2CNR1
SCHEMBL17070413 0.91 RARA (0.34) RARBRARGRARACNR2CNR1
SCHEMBL17070496 0.91 RARB (0.41) RARBRARGRARACNR2CNR1
SCHEMBL19796631 0.91 HTT (0.42) RARBRARGRARACNR2CNR1
SCHEMBL17070405 0.90 RARA (0.34) RARBRARGRARACNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
EP-3730590-A1 LIQUID CRYSTAL MEDIA WITH HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2020-10-28 EP disclosed
US-20200224098-A1 POLYMERIZABLE MONOMER, LIQUID CRYSTAL COMPOSITION USING POLYMERIZABLE MONOMER, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2020-07-16 US disclosed
US-20200208054-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC Corporation (Tokyo) (JP) 2020-07-02 US disclosed
EP-2918658-B1 Liquid crystalline media with homeotropic alignment MERCK PATENT GMBH (DE) 2020-05-13 EP disclosed
US-10513657-B2 Liquid-crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2019-12-24 US disclosed
US-20180057743-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-03-01 US disclosed
US-20180057743-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-03-01 US disclosed
US-9809748-B2 Liquid-crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2017-11-07 US disclosed
US-9809748-B2 Liquid-crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2017-11-07 US disclosed
EP-2918658-A2 Liquid crystalline media with homeotropic alignment Merck Patent GmbH (DE) 2015-09-16 EP disclosed
US-20150252265-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2015-09-10 US disclosed
US-20150252265-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2015-09-10 US disclosed