SCHEMBL17070902

SCHEMBL17070902

CCCCc1c(O)n(C)c(=O)n(C)c1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.51
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP2C9 P11712 1/20 0.51
LMNA P02545 2/20 0.40
HPGD P15428 2/20 0.40
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
HSD17B10 Q99714 1/20 0.37
TYR P14679 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
RECQL P46063 1/20 0.36
NPC1 O15118 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GPR84 Q9NQS5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2199971 0.95 KDM4E (0.54) KDM4EALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL10838932 0.78 CYP1A2 (0.43) KDM4EALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL73817 0.76 PDE4A (0.35) KDM4EALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL10020194 0.73 AOC3 (0.51) KDM4EALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL10216413 0.69 MAPT (0.44) KDM4EALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL1861019 0.67 MAPT (0.43) KDM4EALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL12432434 0.66
SCHEMBL22319318 0.66 KDM4E (0.75) KDM4EALDH1A1CYP1A2CYP2C19CYP2C9
SCHEMBL29392044 0.66 KDM4E (0.75) KDM4EALDH1A1CYP1A2CYP2C19CYP2C9
SCHEMBL10997075 0.63 ALDH1A1 (0.44) KDM4EALDH1A1MAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-20150253479-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed
US-20150253479-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed