SCHEMBL1707183

SCHEMBL1707183

CCC(C)CNC(=O)c1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 4/20 0.57
CTSL P07711 1/20 0.57
PTPN13 Q12923 1/20 0.57
TERT O14746 2/20 0.54
NPC1 O15118 2/20 0.53
RAB9A P51151 1/20 0.53
ATM Q13315 1/20 0.53
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 1/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.53
PKM P14618 1/20 0.53
HPGD P15428 1/20 0.53
GRIN1 Q05586 1/20 0.52
GRIN2A Q12879 1/20 0.52
GRIN2B Q13224 1/20 0.52
NAMPT P43490 2/20 0.52
TTR P02766 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15090069 0.84 PTPRC (0.62) PTPRCCTSLPTPN13TERTNPC1
SCHEMBL15087829 0.84 PTPRC (0.62) PTPRCCTSLPTPN13TERTNPC1
SCHEMBL17865782 0.80 NAMPT (0.58) NPC1RAB9AKMT2AALDH1A1HSD17B10
SCHEMBL13044613 0.79 NAMPT (0.53) NPC1RAB9AKMT2AHSD17B10MEN1
SCHEMBL13875721 0.79 GRIN1 (0.67) PTPRCCTSLPTPN13TERTNPC1
SCHEMBL19349021 0.79 NAMPT (0.58) NPC1RAB9AKMT2AALDH1A1HSD17B10
SCHEMBL799425 0.79 NAMPT (0.58) NPC1RAB9AKMT2AALDH1A1HSD17B10
SCHEMBL17715139 0.78 PTPRC (0.60) PTPRCCTSLPTPN13TERTNPC1
SCHEMBL20613609 0.78 GRIN1 (0.62) PTPRCCTSLPTPN13TERTNPC1
SCHEMBL15082756 0.78 TERT (0.61) PTPRCCTSLPTPN13TERTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9694103-B2 Photochemical activation of surfaces for attaching biomaterial THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2017-07-04 US disclosed
US-9694103-B2 Photochemical activation of surfaces for attaching biomaterial THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2017-07-04 US disclosed
US-20130243862-A1 PHOTOCHEMICAL ACTIVATION OF SURFACES FOR ATTACHING BIOMATERIAL THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2013-09-19 US disclosed
US-20120089222-A1 Photo-Activated Attachment Of Cholesterol To Polyurethane Surfaces For Adhesion Of Endothelial Cells THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2012-04-12 US disclosed
US-20120089222-A1 Photo-Activated Attachment Of Cholesterol To Polyurethane Surfaces For Adhesion Of Endothelial Cells THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2012-04-12 US disclosed
US-7834067-B2 Pigment composition, ink composition, printed article, inkjet recording method and polyallylamine derivative FUJIFILM CORPORATION (JP) 2010-11-16 US disclosed
US-20090233062-A1 PIGMENT COMPOSITION, INK COMPOSITION, PRINTED ARTICLE, INKJET RECORDING METHOD AND POLYALLYLAMINE DERIVATIVE FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed