Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 15/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2340421 | 1.00 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5473748 | 1.00 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Bromide SCHEMBL417945 | 0.99 | CHRM3 (0.43) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Iodide SCHEMBL5386794 | 0.99 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL1997630 | 0.99 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8449813 | 0.99 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7142072 | 0.99 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7143841 | 0.99 | CHRM3 (0.42) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Bromide SCHEMBL1996228 | 0.99 | CHRM3 (0.43) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Bromide SCHEMBL2335688 | 0.99 | CHRM3 (0.43) | CHRM3CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401740-A1 | METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC COPD WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | SUNOVION RESPIRATORY DEVELOPMENT INC. (US) | 2021-12-30 | — | — | US | disclosed |
| CN-113476429-A | Inhalation particles comprising a combination of an anticholinergic, a corticosteroid and a beta-adrenergic agent | 奇斯药制品公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113143894-A | Stable pressurized aerosol solution compositions of glycopyrronium bromide and formoterol in combination | 奇斯药制品公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-105848641-B | Stable pressurized aerosol solution compositions of glycopyrronium bromide and formoterol in combination | 奇斯药制品公司 | 2021-07-09 | — | — | CN | disclosed |
| US-10940110-B2 | Method and system for the treatment of chronic COPD with nebulized anticholinergic administrations | SUNOVION RESPIRATORY DEVELOPMENT INC. (US) | 2021-03-09 | — | — | US | disclosed |
| CN-111150728-A | Stable pressurized aerosol solution compositions of glycopyrronium bromide and formoterol in combination | 奇斯药制品公司 | 2020-05-15 | — | — | CN | disclosed |
| EP-3151812-B1 | INHALATION PARTICLES COMPRISING A COMBINATION OF AN ANTICHOLINERGIC, A CORTICOSTEROID AND A BETA-ADRENERGIC | CHIESI FARM SPA (IT) | 2020-04-22 | — | — | EP | disclosed |
| US-20190254967-A1 | METHOD AND SYSTEM FOR THE TREATMENT OF CHROIC COPD WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | ELEVATION PHARMACEUTICALS, INC. | 2019-08-22 | — | — | US | disclosed |
| EP-3311820-A1 | METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | Sunovion Respiratory Development Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| US-20170202787-A1 | TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED BETA 2-AGONIST OR COMBINED NEBULIZED BETA 2-AGONIST AND ANTICHOLINERGIC ADMINISTRATION | ELEVATION PHARMACEUTICALS, INC. | 2017-07-20 | — | — | US | disclosed |
| US-20140255491-A1 | Method and System For the Treatment of Chronic Obstructive Pulmonary Disease With Nebulized Anticholinergic Administrations | SUNOVION RESPIRATORY DEVELOPMENT INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140018406-A1 | Treatment of Chronic Obstructive Pulmonary Disease With Nebulized Beta 2-Agonist or Combined Nebulized Beta 2-Agonist and Anticholinergic Administration | SUNOVION RESPIRATORY DEVELOPMENT, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| EP-2440196-A1 | TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED BETA 2-AGONIST OR COMBINED NEBULIZED BETA 2-AGONIST AND ANTICHOLINERGIC ADMINISTRATION | Elevation Pharmaceuticals, Inc. (US) | 2012-04-18 | — | — | EP | disclosed |
| US-20110132355-A1 | TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED BETA 2-AGONIST OR COMBINED NEBULIZED BETA 2-AGONIST AND ANTICHOLINERGIC ADMINISTRATION | SUNOVION RESPIRATORY DEVELOPMENT INC. | 2011-06-09 | — | — | US | disclosed |
| WO-2010144628-A2 | TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED BETA 2-AGONIST OR COMBINED NEBULIZED BETA 2-AGONIST AND ANTICHOLINERGIC ADMINISTRATION | ELEVATION PHARMACEUTICALS, INC. (US) | 2010-12-16 | — | — | WO | disclosed |
| EP-2257172-A2 | METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | Elevation Pharmaceuticals, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20100055045-A1 | METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | SUNOVION RESPIRATORY DEVELOPMENT INC. | 2010-03-04 | — | — | US | disclosed |
| WO-2009134524-A2 | METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | ELEVATION PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |
| US-20090215734-A1 | METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | ELEVATION PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| EP-1371645-A1 | Process for the preparation of the 2'-(R)-Glycopyrronium Enantiomers and their use in medicaments | Noe, Christian R. (AT) | 2003-12-17 | — | — | EP | disclosed |