Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944387 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL29702562 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL29407920 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL13830553 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL31045201 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL13044089 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL13401540 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL3193169 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL29580018 | 0.91 | CASP3 (0.55) | CASP3MDM2TLR2 | |
| SCHEMBL21738585 | 0.90 | CASP3 (0.57) | CASP3MDM2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | CD44, EPCAM, ABCG2 | CASP3 2480/4885MDM2 1129/4885TLR2 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.