Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602372 | 0.89 | ALDH1A1 (0.49) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL27558665 | 0.84 | CYP17A1 (0.58) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL27495104 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL28178916 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL22468498 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL10627607 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HTTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL2954086 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL18368418 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL11228700 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HTTLMNAMAPK1POLB | |
| SCHEMBL9683295 | 0.77 | MAPK1 (0.51) | ALDH1A1HTTLMNAMAPK1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015134923-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION (US) | 2015-09-11 | — | — | WO | disclosed |