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Sugi Predict / Compounds / SCHEMBL17073293

SCHEMBL17073293

SCHEMBL17073293

C1=Cc2c(sc3c(-c4cccc(-c5ccc6c7ccccc7c7ccc(-c8cccc(-c9cccc%10c9sc9ccccc9%10)c8)cc7c6c5)c4)cccc23)CC1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.46
▸ PRKDC P78527 3/20 0.39
▸ PARP14 Q460N5 1/20 0.32
▸ DNPH1 O43598 1/20 0.32
▸ PIM3 Q86V86 1/20 0.32
▸ PIK3CD O00329 1/20 0.31
▸ BRD4 O60885 1/20 0.31
▸ PIK3CA P42336 1/20 0.31
▸ PIK3CB P42338 1/20 0.31
▸ MTOR P42345 1/20 0.31
▸ PIK3CG P48736 1/20 0.31
▸ KCNH2 Q12809 1/20 0.31
▸ BRDT Q58F21 1/20 0.31
▸ LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17779843 0.93 ALOX5 (0.35) ALOX5PRKDCLIMK1
SCHEMBL788882 0.89 ALOX5 (0.39) ALOX5PRKDC
SCHEMBL17425700 0.87 ALOX5 (0.46) ALOX5PRKDCPARP14DNPH1PIK3CD
SCHEMBL25963039 0.86 ALOX5 (0.47) ALOX5PRKDCPARP14PIM3PIK3CD
SCHEMBL20372916 0.85 ALOX5 (0.45) ALOX5PRKDCPARP14PIM3PIK3CD
SCHEMBL18828195 0.85 ALOX5 (0.48) ALOX5PRKDCPARP14PIM3PIK3CD
SCHEMBL22486945 0.84 ALOX5 (0.34) ALOX5PRKDCDNPH1
SCHEMBL18951187 0.83 ALOX5 (0.42) ALOX5PRKDCPARP14PIK3CDBRD4
SCHEMBL18951609 0.83 ALOX5 (0.51) ALOX5PRKDCPARP14DNPH1PIM3
SCHEMBL19596322 0.83 PIM3 (0.37) PIM3LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015134017-A1 PHOSPHORESCENT OLED DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-11 — — WO disclosed