Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16221282 | 0.96 | HTR7 (0.36) | TSHRCLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL25081631 | 0.85 | KDM4E (0.35) | PRMT5WDR77HTR7KDM4E | |
| SCHEMBL16743919 | 0.81 | MCL1 (0.44) | TSHRCLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL20071974 | 0.81 | CYP1A2 (0.49) | TSHRCLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL16135203 | 0.79 | CYP1A2 (0.38) | TSHRCLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL15424779 | 0.78 | CD274 (0.41) | TSHRCLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL17563707 | 0.77 | APP (0.35) | ALOX5APFEN1MCL1TRPA1LMNA | |
| SCHEMBL27565196 | 0.77 | NPC1 (0.38) | TSHRCYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL17641568 | 0.77 | HTR7 (0.38) | TSHRCLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL16135169 | 0.76 | KDM4E (0.33) | TSHRCLK4CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015134017-A1 | PHOSPHORESCENT OLED DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-09-11 | — | — | WO | disclosed |