Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192046 | 0.81 | KIT (0.41) | CTSLCTSBPLK1TLR7HDAC8 | |
| SCHEMBL15680586 | 0.77 | CHRM1 (0.41) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL15680612 | 0.68 | MEN1 (0.40) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL15670843 | 0.67 | HTR4 (0.58) | — | |
| SCHEMBL118088 | 0.64 | MCHR1 (0.53) | APP | |
| SCHEMBL14845182 | 0.64 | PIK3CG (0.52) | CHRM1 | |
| SCHEMBL22836412 | 0.64 | IRAK4 (0.49) | MAP4K3 | |
| SCHEMBL22836180 | 0.63 | IRAK4 (0.45) | MAP4K3KITCSF1R | |
| SCHEMBL14699832 | 0.63 | CXCR4 (0.46) | — | |
| SCHEMBL15671003 | 0.63 | HDAC6 (0.52) | HDAC8CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917223-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | Glaxo Group Limited (GB) | 2015-09-16 | — | — | EP | disclosed |