⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17552593 | 0.72 | — | — | |
| SCHEMBL87230 | 0.72 | — | — | |
| SCHEMBL16955588 | 0.69 | CES2 (0.30) | — | |
| SCHEMBL12108326 | 0.69 | — | — | |
| SCHEMBL12912878 | 0.69 | — | — | |
| SCHEMBL12180002 | 0.67 | — | — | |
| SCHEMBL5327956 | 0.67 | MEN1 (0.33) | — | |
| SCHEMBL7331924 | 0.67 | — | — | |
| SCHEMBL18885186 | 0.67 | — | — | |
| SCHEMBL2878346 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126987-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2015-09-08 | — | — | US | disclosed |
| EP-2091948-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2012-04-18 | — | — | EP | disclosed |
| EP-2091948-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | Probiodrug AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| US-20080214620-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-09-04 | — | — | US | disclosed |
| US-7417100-B2 | Transparent fluorine-containing copolymer | CENTRAL GLASS COMPANY, LIMITED (JP) | 2008-08-26 | — | — | US | disclosed |
| WO-2008065141-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-06-05 | — | — | WO | disclosed |
| US-7060771-B2 | Transparent fluorine-containing copolymer | CENTRAL GLASS COMPANY, LIMITED (JP) | 2006-06-13 | — | — | US | disclosed |
| US-20060063902-A1 | Transparent fluorine-containing copolymer | CENTRAL GLASS CO., LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| US-20030236369-A1 | Transparent fluorine-containing copolymer | CENTRAL GLASS COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |